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Using the mutated version of herpes simplex virus-1 (HSV1) to target and terminate CD133+ cancer stem cells.
Novel acetylcholinesterase (AChE) inhibitors for the symptomatic treatment of Alzheimer's disease.
The present invention involves compounds that that demonstrate predominant activity against replicating Mtb, non-replicating Mtb, or both replicating and non-replicating Mtb.
The invention involves the successful development of a first-in-class, potent, not generally cytotoxic, chemical probe, that selectively activates the apoptotic but not the adaptive arm of the UPR.
This invention uses microRNA biomarkers to detect or diagnose Barrett's esophagus, detect dysplasia in Barrett's esophagus, and detect early onset of esophageal cancer.
This invention is aimed at delaying the tumor growth in breast and ovarian cancers by increasing BRCA1 protein expression.
This invention offers a novel approach to the prevention of lung cancer via the selective inhibition of the enzyme in the human lung that activates tobacco compounds into carcinogens.
Implantable biomaterial for promoting bone and cartilage regeneration in joints following articular cartilage injury, a leading cause of advanced osteoarthritis.
The invention is a novel synthesis procedure to create hydrogels with mechanical properties desirable for musculoskeletal tissue engineering.
Based on precision drug delivery technologies, ConocoPhilips and KU have jointly developed a patented technology using polyelectrolyte complex (PEC) nanoparticles to entrap/protect and delay the release of oil and gas field chemicals.